CENFORCE-D is manufactured by Centurion Laboratories in India and is a combination drug containing 100mg of Sildenafil Citrate and 60mg of Dapoxetine hydrochloride, used in the treatment of erectile dysfunction and premature ejaculation in men 18 to 64 years of age. It helps men get and maintain erection and improve ejaculation time.
Sildenafil Citrate belongs to the drug class called phosphodiesterase type 5 (PDE5) inhibitors. It works in helping men get and maintain an erection by increasing blood flow to the penis following sexual stimulation.
Dapoxetine on the other hand, is a serotonin-norepinephrine reuptake inhibitor (SNRI), an antidepressant that increases serotonin and norepinephrine levels. Serotonin is a neurotransmitter that is responsible in sending nerve messages that results in many body functions including ejaculation. Dapoxetine is a drug used in premature ejaculation. Premature ejaculation is a disorder where a man ejaculates before, during or shortly after penetration with minimal sexual stimulation even before a man even desires to do so. This drug improves control over ejaculation and increase time to ejaculation by increasing serotonin activity in the nervous system, delaying ejaculation reflex.

How to use:

CENFORCE-D 160mg (Sildenafil and Dapoxetine Citrate Tablets) preparation should be taken 50-60 minutes before sexual intercourse. One tablet can increase the duration of sexual intercourse several times. Means for potency can be taken daily. The maximum concentration of active substances in the blood is achieved after about 4 hours, and the generic action calculated for at least 8-10 hours. CENFORCE-D 160mg (Sildenafil and Dapoxetine Citrate Tablets) taken orally once a day 1, and washed down with water. One can start at half dose tablets. An hour later, the drug starts to be effective, and the man will feel the blood flow to the genitals, feels that he is able to conduct long-term and high-quality sexual intercourse. On the activity of the active ingredients affect alcoholic beverages and alcohol, which slow down the onset of effect.

It is worth noting that CENFORCE-D drug will result only if there is a natural sexual arousal and stimulation.

Contraindications:

CENFORCE-D is contraindicated to patients allergic to any of the active ingredients, Sildenafil or Dapoxetine, and to any of the inactive ingredients of the tablet.

This drug is also contraindicated to patients the following medical conditions:

Heart problems and blood pressure disorder
Moderate to severe liver impairment
Leukemia, sickle-cell anemia
Myeloma
Deformity of penis
History of mania, hypomania or bipolar disorder
Epilepsy

CENFORCE-D must not be used by patients taking the following medications:

Monoamine Oxidase Inhibitors (MAOIs)
Serotonin Reuptake Inhibitors
CYP inhibitors
Recreational drugs
Guanylate cyclase stimulators
Nitrates of any form

CENFORCE-D is also contraindicated to patients not allowed to engage in sexual activity due to cardiovascular conditions.

Side effects

The following side effects are the most commonly reported:

Headache
Nausea
Dizziness
Diarrhea

Other side effects include, but not limited to:

Vision changes
Fatigue
Mental, mood changes
Decreased libido
Hyperhidrosis
Nasal congestion
Myalgia
Insomnia
Fainting

A physician must be notified if any of the side effects above persist or become worse.

The use of CENFORCE-D must be stopped and medical attention must be sought if the following side effects occur:

Seizure
Sudden decrease or loss of hearing
Sudden vision loss in one or both eyes
Mania/hypomania
Bipolar disorder

Severe allergic reaction with symptoms of hives, breathing difficulty and swelling of face, throat, tongue and lips

Side effects of Cenforce D160mg are not limited to the lists above. An urgent medical attention is needed if an erection lasts for more than 4 hours or if an erection is painful. Permanent damage to the penis may happen if these side effects are ignored. Alcohol consumption must be avoided while taking CENFORCE-D for it may increase side effects such as dizziness, drowsiness, slow reflexes and impaired judgement. Combination of this drug and alcohol may also increase the risk of accidental injury due to an adverse effect such as syncope.

Warnings and Precautions

A patient must inform a healthcare professional of all current medical conditions, personal or family medical history, all current medications and previously used medications to determine the safety of the drug. Caution is advised to men with the following medical conditions:

Mild to moderate kidney problems
Underlying signs of depression
Raised intraocular pressure or with risk of angle-closure glaucoma
History of non-arteritic anterior ischemic optic neuropathy (naion)

CENFORCE-D can interact with the following medications and cause undesirable effects:

Drugs that affect platelet function
Alpha blockers and other hypotensive drugs
Some antibiotics
Other drugs for erectile dysfunction
Antifungal drugs

CENFORCE-D must not be used concomitantly with other drugs used to treat erectile dysfunction or drugs for prostate disorders.